Clinically Relevant Ingredients, Working Together
Every ingredient is selected for its role in a specific metabolic pathway - glucoseregulation, insulin function, gut-metabolic health, or post-meal balance, so each oneearns its place.
GlucoVantage® Dihydroberberine
A patented, highly bioavailable form of berberine with up to 5× greater absorption than
standard berberine. Activates AMPK - the body's metabolic master switch - to support
healthy blood sugar levels, insulin sensitivity, and glucose disposal, including through
GLP-1 modulation.
CoreBiome® Tributyrin
A clinically tested, patented tributyrin that delivers butyrate to both the small and large
intestine - unlike sodium butyrate, which is absorbed before reaching the colon.
Supports gut barrier integrity, microbiome balance, and the gut-metabolism axis
Banaba Leaf Extract
Standardized for corosolic acid, which supports glucose uptake pathways and helps
moderate post-meal blood sugar excursions.
Ceylon Cinnamon
Rich in bioactive polyphenols that support healthy insulin signaling, glucose
metabolism, and antioxidant function.
Chromium Picolinate
An essential trace mineral that supports normal insulin function and healthy
macronutrient metabolism, contributing to stable glucose utilization.
Gymnema Sylvestre
Traditionally used to support carbohydrate metabolism by influencing intestinal glucose
absorption and sweet taste receptor signaling - helping moderate sugar intake
naturally.
Salacia Reticulata
Contains naturally occurring compounds that slow carbohydrate breakdown,
supporting smoother post-meal glucose responses.
GlucoVantage® is a registered trademark of NNB Nutrition. Patented — see nnbnutrition.com/patents
CoreBiome® is a registered trademark and protected by U.S. Patents 11,045,509 and 11,141,442 under exclusive global distribution by Compound Solutions, Inc.
Powerful Ingredients You Can Trust
Each gummy combines four science-backed botanicals and minerals for comprehensive blood sugar support.
Ceylon Cinnamon
Supports wellness & metabolic balance
Chromium
Helps support nutrient utilization & energy balance
Banaba
Helps support glucose transport and healthy sugar balance after meals
Salacia Reticulata
Helps support carbohydrate metabolism and steady energy after meals
Dihydroberberine (GlucoVantage®) — 150 mg
What it is:
A reduced, more bioavailable form of berberine that is absorbed more efficiently in the gut.
Why it's included:
Standard berberine has notoriously poor absorption. Dihydroberberine addresses this limitation, delivering significantly more active compound to circulation.
How it supports the formula:
Human pharmacokinetic studies show ~5× greater absorption and ~20× greater systemic exposure compared to standard berberine, enabling effective metabolic support at a lower dose.
Berberine Phytosome (Berbevis®) — 250 mg
What it is:
Berberine bound to phospholipids using patented Phytosome® technology for enhanced delivery.
Why it's included:
The phospholipid complex improves intestinal absorption and systemic availability of berberine.
How it supports the formula:
Clinical studies demonstrate up to ~10× higher bioavailability, enabling effective once-daily dosing while maximizing the metabolic benefits of berberine.
Tributyrin (CoreBiome®) — 300 mg
What it is:
A stable, triglyceride form of butyrate that survives digestion to reach the lower intestine.
Why it's included:
Butyrate is widely studied for its role in gut barrier integrity and metabolic signaling, but free butyrate is rapidly absorbed in the upper GI tract.
How it supports the formula:
Tributyrin delivers butyrate where it's most effective—the lower intestine—supporting gut health and contributing to the formula's dual-action metabolic approach.
Banaba Leaf Extract (2% Corosolic Acid) — 100 mg
What it is:
An extract from Lagerstroemia speciosa standardized to 2% corosolic acid.
Why it's included:
Banaba has been traditionally used and studied for its role in supporting healthy glucose metabolism.
How it supports the formula:
Corosolic acid complements berberine's AMPK-activating effects, providing additional support for metabolic health through a complementary mechanism.
Chromium Picolinate — 200 mcg
What it is:
A highly bioavailable form of the essential trace mineral chromium.
Why it's included:
Chromium is an essential nutrient that plays a role in insulin signaling and glucose metabolism.
How it supports the formula:
At 200 mcg (571% DV), chromium picolinate provides meaningful support for metabolic health, complementing the berberine and tributyrin in the formula.